GlobalHealthCuratedmedium confidence

Antimicrobial Resistance

Drug-resistant infections already kill more than HIV or malaria and are projected to accelerate sharply.

Severity score

76.3

Critical · default weighting

Trajectory

Worsening

What this is

Bacteria, fungi and parasites are increasingly resistant to the drugs used to treat them, driven by over-prescription in humans and heavy prophylactic use in agriculture. AMR is a slow-moving structural threat: it makes routine surgery, chemotherapy and childbirth progressively more dangerous. Because deaths are recorded under the underlying infection, AMR mortality is estimated statistically rather than counted directly.

Score breakdown

Loss of life

85

Direct and attributable mortality, normalised across annual and cumulative tolls.

Lives negatively impacted

80

People displaced, injured, food-insecure, exposed or otherwise materially harmed.

Financial cost

80

Direct damage, lost output and health-system spend attributable to the event.

Environmental impact

40

Emissions, habitat and biodiversity loss, contamination and irreversibility.

Trajectory

88

Whether the situation is escalating, and how much worse it is plausibly getting.