The Threat List

Status:Health

GlobalHealthDeep-sourcedhigh confidence

Global Cancer Burden

The second largest cause of death worldwide, rising as populations age and screening lags in poorer countries.

Severity score

68.2

Critical · default weighting

Trajectory

Worsening

How this is ranked

What this is

Cancer causes close to ten million deaths a year, with the fastest growth in low and middle income countries where diagnosis comes late and treatment is scarce. Tobacco, obesity, infection and air pollution drive a large and preventable share of cases. Survival gaps between rich and poor countries are among the widest in medicine.

Score breakdown

Each factor is a 0–100 relative severity index, not the raw figure or a specific time period. The actual counts and periods are listed under "Standardized Impact" on the right.

Loss of life

92

Direct and attributable mortality, normalised across annual and cumulative tolls.

Lives negatively impacted

80

People displaced, injured, food-insecure, exposed or otherwise materially harmed.

Financial cost

74

Direct damage, lost output and health-system spend attributable to the event.

Environmental impact

4

Emissions, habitat and biodiversity loss, contamination and irreversibility.

Trajectory

52

Whether the situation is escalating, and how much worse it is plausibly getting.

Audit trail

Everything this entry has been through — when it was first searched for, queued, reviewed and approved, and how its figures and rank have moved since.

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