The Threat List

Status:Health

GlobalHealthDeep-sourcedhigh confidence

Tuberculosis

The deadliest infectious disease in the world, curable but persistently underfunded.

Severity score

55.2

Severe · default weighting

Trajectory

Improving

How this is ranked

What this is

Tuberculosis remains the leading cause of death from a single infectious agent. It is curable with a months-long drug regimen, but detection gaps, treatment interruption, HIV co-infection and rising multidrug resistance keep the toll high. The burden is concentrated in India, Indonesia, China, the Philippines, Pakistan, Nigeria, Bangladesh and South Africa.

Score breakdown

Each factor is a 0–100 relative severity index, not the raw figure or a specific time period. The actual counts and periods are listed under "Standardized Impact" on the right.

Loss of life

88

Direct and attributable mortality, normalised across annual and cumulative tolls.

Lives negatively impacted

72

People displaced, injured, food-insecure, exposed or otherwise materially harmed.

Financial cost

35

Direct damage, lost output and health-system spend attributable to the event.

Environmental impact

5

Emissions, habitat and biodiversity loss, contamination and irreversibility.

Trajectory

30

Whether the situation is escalating, and how much worse it is plausibly getting.

Audit trail

Everything this entry has been through — when it was first searched for, queued, reviewed and approved, and how its figures and rank have moved since.

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